Formulation and Control of a Topical Emulsion, Containing Algerian Vitis vinifera.L Leaves Extract

Topical emulsions find their applications in wrinkle reduction (skin aging), acne treatment and, sebum secretions regulation. For various dermatological affections, many topical formulations like sunscreens and anti-aging creams are prepared using plant-based ingredients
 The objective of this study was to formulate an emulsion containing Vitis vinifera. L leaves extract, evaluate its stability antioxidant activity vitro.A spectrophotometric assay the main phenolic groups for 10 leave samples performed.O/W were a nonionic surfactant polysorbate 80.1,1-diphenyl-2-picrylhydrazyl performed plant extracts activity. 
 Physical stored at 25 ºC 40 60 days assessed based on physico-chemical characteristics including color, creaming, liquefaction, centrifugation pH, electrical conductivity.
 showed good physical properties pharmaceutical stability. polyphenol-rich-plant-derived extract activities. research allowed development which can be proposed use. However, vivo studies recommended confirm action cream.